Journal issues > Issue , > Reactivations of prior infections in cancer patients treated with immunosuppressive/immunomodulatory treatments

Reactivations of prior infections in cancer patients treated with immunosuppressive/immunomodulatory treatments

By: D. Schrijvers MD, PhD

SUMMARY

Prior infections may reactivate in cancer patients receiving immunosuppressive/immunomodulatory treatments. Depending on the severity of the immune suppression, chemoprophylaxis may be necessary and is recommended in Herpes simplex virus- and Herpes zoster virus-seropositive patients undergoing allogenous hematologic stem cell transplantation and in solid cancer patients with Hepatitis B surface antigen or hepatitis B core antibody seropositivity.

For other infections, a low threshold for performing diagnostic testing of potential viral or tuberculosis infections should be used should be used in daily clinical practice in order to prevent severe morbidity or mortality.

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