Articles

5-Fluorouracil-induced pericarditis: case report and literature survey

BJMO - volume 10, issue 1, february 2016

S. Maréchal MD, G. Houbiers MD, M-P. Graas MD, C. Focan MD, PhD

Summary

5-Fluorouracil is an antimetabolite frequently used in the treatment of digestive cancers. Outside well-known side effects, it may induce cardiac toxicity under various clinical forms, from chest pain to arrhythmia, or even cardiac arrest, pericarditis being one of the most uncommon.1,2 We report here the case of a 52-year-old man who developed pericarditis symptoms after continuous 5-fluorouracil infusions.

(BELG J MED ONCOL 2016;10(1):35–37)

Read more