BJMO - volume 13, issue 6, october 2019
S. Dingenen MD, L. Renard MD, T.M. Lawson MD, N. Whenham MD
SUMMARY
This review is designed to help the management of low grade glioma and is based on literature regarding molecular characterisation, surgery, radiotherapy, chemotherapy and neurocognitive preservation.
(BELG J MED ONCOL 2019;13(6): 213–218)
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BJMO - volume 12, issue 1, february 2018
C. van Marcke MD, L. Renard MD, F.P. Duhoux MD, PhD
Summary
Patients with HER2-positive advanced breast cancer frequently develop brain metastases. Dual anti-HER2 therapy significantly prolongs survival in previously untreated metastatic disease. However, no safety data exist on the concurrent use of pertuzumab, trastuzumab and brain radiotherapy. We describe two cases of previously untreated HER2-positive breast cancer and brain metastases, who developed acute cerebral toxicity during the concomitant administration of anti-HER2 therapy and whole-brain radiotherapy. Systematic clinical data is warranted to prove the safety of this association.
(BELG J MED ONCOL 2018;12(1):22–25)
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