BJMO - 12, issue 3, february 2018
J. Mebis MD, PhD, S. Censabella , S. Engels , C. Van Narsenille , G. Orye , S. Marquette , L. Vansteelant , L. Noé , A. Maes MD, P. Bulens , E.J.R. Joosens , D. Luyten MD
BJMO - volume 11, issue 8, december 2017
J. Robijns , S. Censabella , P. Bulens , A. Maes MD, L. Noé , M. Brosens , L. Van den Bergh MD, PhD, S. Claes , J. Mebis MD, PhD
Photobiomodulation therapy is based on the application of visible and/or (near-)infrared light on the target tissue. We performed a review of 34 articles on the use of photobiomodulation therapy in the management of cancer related lymphoedema, oral mucositis, radiodermatitis, chemotherapy-induced peripheral neuropathy, osteonecrosis of the jaw, and xerostomia/hyposalivation. The findings suggest that photobiomodulation therapy is a promising option for the management of these cancer therapy-related side effects.
(BELG J MED ONCOL 2017;11(8):364–374)
Read moreBJMO - volume 10, issue 7, november 2016
A. Awada MD, PhD, J.F. Baurain MD, PhD, P. Clement MD, PhD, P. Hainaut MD, PhD, S. Holbrechts MD, PhD, J-M. Hougardy , K. Jochmans MD, PhD, V. Mathieux MD, PhD, J. Mebis MD, PhD, M. Strijbos MD, PhD, C. Vulsteke MD, PhD, P. Verhamme MD, PhD
Venous thrombosis is a common complication in cancer patients and thromboembolism is the second most common cause of death. Several practice guidelines provide recommendations for the management of cancer-associated thrombosis. However, these guidelines do not sufficiently cover commonly encountered clinical challenges. With this expert panel, consisting of medical oncologists, haematologists, internists and thrombosis specialists, we aimed to develop a practical Belgian guidance for adequate prevention and treatment of cancer-associated thrombosis that covered several challenging situations encountered in daily clinic. This paper discusses the following topics: type and treatment duration of anticoagulant therapy, recurrent VTE despite anticoagulation, anticoagulation in case of renal impairment, liver disease and thrombocytopenia, the role of anti-Xa monitoring, central venous catheter-associated thrombosis, the position of direct oral anticoagulants and thromboprophylaxis, both in ambulatory and hospitalised patients. For an overview of the recommendations formulated by the expert panel, we refer to the key messages for clinical practice in this article.
(BELG J MED ONCOL 2016;10(7):249–255)
Read moreBJMO - volume 9, issue 2, may 2015
I. Elalamy MD, PhD, J-L. Canon MD, PhD, A. Bols MD, PhD, W. Lybaert MD, L. Duck MD, PhD, K. Jochmans MD, PhD, L. Bosquée MD, PhD, M. Peeters MD, PhD, A. Awada MD, PhD, P. Clement MD, PhD, S. Holbrechts MD, PhD, J.F. Baurain MD, PhD, J. Mebis MD, PhD, J. Nortier MD, PhD
Venous thromboembolism is a frequent cause of mortality and morbidity in patients with malignancy. Thrombosis is one of the leading causes of death in patients with malignancy after cancer itself. As such, prompt recognition and treatment of venous thromboembolism are required in order to reduce the risk of venous thromboembolism-related mortality. This report reviews the interrelationship between cancer, renal insufficiency and venous thromboembolism. The working group behind this review article concludes that low molecular weight heparins decrease the risk of recurrent venous thrombosis in cancer patients without increasing major bleeding complications. Low molecular weight heparins are therefore recommended as first line antithrombotic treatment in cancer patients with a clear clinical benefit. In patients with renal dysfunction, who are at increased risk of bleeding and of thrombotic complications, preference should be given to unfractionated heparin or a low molecular weight heparin with a mean molecular weight such as tinzaparin, having less risk of plasma accumulation and offering the possibility to maintain full therapeutic dose.
(BELG J MED ONCOL 2015;9(2):53–60)
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