Evans blue as a diagnostic tool for non-muscle-invasive bladder cancer: a preclinical study

BJMO - volume 10, issue 7, november 2016

S. Elsen PhD, E. Lerut MD, PhD, B. Van Cleynenbreugel MD, PhD, F. Van der Aa MD, PhD, H. Van Poppel MD, PhD, P.A. de Witte PhD


The diagnosis of non-muscle-invasive bladder cancer using the standard white-light cystoscopy technique is not optimal and leads to underdiagnosis of some of the tumours. Therefore, in this thesis, the use of Evans blue dye as a diagnostic tool to aid bladder cancer detection during white-light cystoscopy was investigated using a rat orthotopic bladder cancer model. The results show that Evans blue might have great potential to assist detection of bladder cancer in a clinical setting.

(BELG J MED ONCOL 2016;10(7):281–284)

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